Livedoid vasculitis

From WikiMD's Wellness Encyclopedia

(Redirected from PURPLE syndrome)

Livedoid Vasculitis (also known as Livedo Vasculitis or Atrophie Blanche) is a rare skin condition characterized by small, painful ulcers and extensive scarring on the lower legs. It is a form of vasculitis (inflammation of blood vessels) that affects the small blood vessels in the skin.

Symptoms[edit | edit source]

The primary symptom of Livedoid Vasculitis is painful skin ulcers, primarily on the lower legs. These ulcers are often surrounded by a livedo reticularis pattern, a mottled discoloration of the skin. Other symptoms may include pain, itching, and burning in the affected areas.

Causes[edit | edit source]

The exact cause of Livedoid Vasculitis is unknown. However, it is believed to be related to blood clotting disorders, as many patients with the condition have been found to have abnormalities in their blood clotting mechanisms. Other potential causes include autoimmune diseases, infections, and certain medications.

Diagnosis[edit | edit source]

Diagnosis of Livedoid Vasculitis is typically made based on the characteristic skin findings. A biopsy of the affected skin may also be performed to confirm the diagnosis. Additional tests may be done to rule out other conditions and to identify any underlying blood clotting disorders.

Treatment[edit | edit source]

Treatment of Livedoid Vasculitis primarily involves managing the symptoms and preventing the formation of new ulcers. This may include the use of topical creams, pain medication, and anticoagulants to prevent blood clots. In severe cases, immunosuppressive drugs may be used to reduce inflammation.

Prognosis[edit | edit source]

The prognosis for Livedoid Vasculitis varies. Some patients may experience a complete resolution of symptoms, while others may have recurring episodes of ulcers. In severe cases, the condition can lead to significant scarring and disability.

See Also[edit | edit source]

Livedoid vasculitis Resources
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Contributors: Prab R. Tumpati, MD