Pancreatic fistula

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD's weight loss doctor NYC
Philadelphia GLP-1 weight loss and GLP-1 clinic NYC

Pancreatic fistula
Synonyms	N/A
Pronounce	N/A
Specialty	N/A
Symptoms	Abdominal pain, nausea, vomiting, fever, jaundice
Complications	Peritonitis, sepsis, abscess formation
Onset	Post-surgical or post-traumatic
Duration	Variable, depending on treatment
Types	N/A
Causes	Pancreatic surgery, abdominal trauma, pancreatitis
Risks	Obesity, smoking, alcohol use disorder
Diagnosis	CT scan, MRI, ERCP
Differential diagnosis	Pancreatitis, bile duct injury, gastrointestinal perforation
Prevention	N/A
Treatment	Nutritional support, drainage, octreotide, surgery
Medication	N/A
Prognosis	Generally good with treatment, but depends on underlying cause
Frequency	Occurs in 5-30% of pancreatic surgeries
Deaths	N/A

Pancreatic fistula is a medical condition characterized by an abnormal connection or passageway between the pancreas and other organs or tissues. This condition is often associated with pancreatic surgery or pancreatitis.

Causes

Pancreatic fistulas can occur as a result of several conditions or procedures. These include:

• Pancreatic surgery: This is the most common cause of pancreatic fistulas. The condition can occur as a complication of surgery to remove a pancreatic tumor or to treat chronic pancreatitis.
• Pancreatitis: Inflammation of the pancreas can lead to the formation of a fistula. This can occur in both acute and chronic forms of the disease.
• Trauma: Injuries to the abdomen can damage the pancreas and lead to the formation of a fistula.

Symptoms

The symptoms of a pancreatic fistula can vary depending on the location and severity of the fistula. Common symptoms include:

• Abdominal pain
• Fever
• Nausea and vomiting
• Weight loss
• Jaundice: This is a yellowing of the skin and eyes that occurs when the liver is unable to properly process bilirubin, a byproduct of red blood cell breakdown.

Diagnosis

Diagnosis of a pancreatic fistula typically involves a combination of physical examination, medical history, and imaging tests. These may include:

• Computed tomography (CT) scan: This imaging test can provide detailed images of the pancreas and surrounding structures, helping to identify a fistula.
• Magnetic resonance imaging (MRI): This test can provide even more detailed images than a CT scan, and is particularly useful for identifying fistulas that connect to the digestive tract.
• Endoscopic retrograde cholangiopancreatography (ERCP): This procedure involves the use of a flexible tube with a light and camera at the end (endoscope) to examine the pancreas and bile ducts. It can also be used to inject dye into these structures, making them easier to see on X-rays.

Treatment

Treatment for a pancreatic fistula depends on the severity and location of the fistula, as well as the patient's overall health. Options may include:

• Surgery: In some cases, surgery may be needed to repair the fistula. This can involve removing the damaged portion of the pancreas, or creating a new connection between the pancreas and the digestive tract.
• Drainage: If the fistula is causing a buildup of fluid in the abdomen, a drain may be inserted to remove this fluid.
• Medication: In some cases, medication may be used to manage symptoms or treat underlying conditions that are contributing to the fistula.

See also

• Pancreas
• Pancreatic surgery
• Pancreatitis
• Trauma (medicine)