Pancreatic polypeptide

Pancreatic polypeptide is a protein secreted by the pancreas, specifically by the PP cells in the Islets of Langerhans. It is part of the polypeptide family of proteins, which also includes neuropeptide Y and peptide YY.

Function

Pancreatic polypeptide regulates the pancreas and gastrointestinal tract. It slows down the secretion of the digestive enzymes from the pancreas and reduces the movement of food through the digestive tract.

Structure

The pancreatic polypeptide is a linear polypeptide that is composed of 36 amino acids. It has a single disulfide bond, which contributes to its structural stability.

Clinical significance

Abnormal levels of pancreatic polypeptide can indicate a problem with the pancreas. For example, increased levels can be a sign of pancreatic tumors, while decreased levels can indicate pancreatic insufficiency or diabetes.

See also

• Pancreas
• Polypeptide
• Neuropeptide Y
• Peptide YY
• Digestive enzymes
• Pancreatic tumors
• Pancreatic insufficiency
• Diabetes

Pancreatic polypeptide Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski