Peliosis hepatis

Peliosis hepatis is a rare, pathological condition where multiple, random, blood-filled cavities occur throughout the liver. The size of these cavities usually ranges from a few millimeters to three centimeters in diameter. Peliosis hepatis was first described in 1861 by Wagner. The term "peliosis" is derived from the Greek word "pelios," which means "dusky" or "livid."

Causes

The exact cause of peliosis hepatis is unknown. However, it has been associated with several conditions and medications. These include:

• Cancer: Peliosis hepatis is often found in patients with malignant tumors, especially lymphoma and leukemia.
• Infections: Certain infections, such as tuberculosis, bacterial endocarditis, and HIV, have been linked to peliosis hepatis.
• Medications: Some drugs, including anabolic steroids, oral contraceptives, and danazol, have been associated with the condition.

Symptoms

Peliosis hepatis often does not cause any symptoms. However, if symptoms do occur, they may include:

• Abdominal pain
• Nausea and vomiting
• Jaundice (yellowing of the skin and eyes)
• Ascites (fluid accumulation in the abdomen)

Diagnosis

Peliosis hepatis is usually diagnosed through imaging studies, such as ultrasound, CT scan, or MRI. A liver biopsy may also be performed to confirm the diagnosis.

Treatment

Treatment for peliosis hepatis depends on the underlying cause. If the condition is caused by a medication, the drug may need to be discontinued. In severe cases, liver transplantation may be necessary.

Prognosis

The prognosis for peliosis hepatis varies depending on the underlying cause and the patient's overall health. In some cases, the condition can resolve on its own without treatment.

See also

• Liver disease
• Hepatic veno-occlusive disease
• Budd-Chiari syndrome

Peliosis hepatis Resources
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