Peter Tontonoz

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Peter Tontonoz

Peter Tontonoz is an American physician-scientist and professor known for his research in the field of molecular biology and lipid metabolism. He is a faculty member at the David Geffen School of Medicine at UCLA and a member of the Howard Hughes Medical Institute.

Early Life and Education[edit | edit source]

Peter Tontonoz was born in New York City. He completed his undergraduate studies at Harvard University, where he earned a degree in Biochemistry. He then pursued his medical degree (M.D.) and a Ph.D. in Cell Biology at the Harvard Medical School.

Research and Career[edit | edit source]

Tontonoz's research primarily focuses on the regulation of lipid metabolism and its implications for cardiovascular disease and metabolic disorders. His work has significantly contributed to the understanding of the role of nuclear receptors in lipid metabolism.

Key Contributions[edit | edit source]

  • **Nuclear Receptors**: Tontonoz has extensively studied the role of nuclear receptors, particularly the peroxisome proliferator-activated receptors (PPARs) and liver X receptors (LXRs), in the regulation of lipid metabolism.
  • **Lipid Metabolism**: His research has elucidated the mechanisms by which lipid metabolism is regulated at the molecular level, providing insights into the development of atherosclerosis and other metabolic diseases.
  • **Gene Regulation**: Tontonoz has also explored how nuclear receptors regulate gene expression and how this regulation impacts cholesterol and fatty acid homeostasis.

Awards and Honors[edit | edit source]

Peter Tontonoz has received numerous awards for his contributions to science, including:

Personal Life[edit | edit source]

Tontonoz resides in Los Angeles, California, where he continues his research and teaching at UCLA. He is married and has two children.

Related Pages[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]


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Contributors: Prab R. Tumpati, MD