Plasmacytosis

Plasmacytosis is a medical condition characterized by an abnormal increase in the number of plasma cells in the blood. Plasma cells are a type of white blood cell that produce antibodies to fight off infections. Plasmacytosis can occur in various diseases, including multiple myeloma, Waldenström's macroglobulinemia, and certain types of autoimmune diseases.

Causes

Plasmacytosis can be caused by a variety of conditions. The most common cause is multiple myeloma, a type of cancer that begins in the plasma cells. Other causes can include autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, and infections, such as HIV and hepatitis C.

Symptoms

The symptoms of plasmacytosis can vary depending on the underlying cause. In multiple myeloma, symptoms can include bone pain, fatigue, and frequent infections. In autoimmune diseases, symptoms can include joint pain, fever, and rash. In infections, symptoms can include fever, fatigue, and weight loss.

Diagnosis

Plasmacytosis is typically diagnosed through a blood test that measures the number of plasma cells in the blood. Other tests, such as a bone marrow biopsy, may also be used to confirm the diagnosis and determine the underlying cause.

Treatment

The treatment for plasmacytosis depends on the underlying cause. In multiple myeloma, treatment options can include chemotherapy, radiation therapy, and stem cell transplant. In autoimmune diseases, treatment can include corticosteroids and other immunosuppressive drugs. In infections, treatment can include antiviral drugs or antibiotics.

See also

• Plasma cell
• Multiple myeloma
• Autoimmune disease