Porokeratosis

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Obesity, Sleep & Internal medicine
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Porokeratosis
Porokeratosis
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Skin lesions, itching, burning sensation
Complications Skin cancer
Onset Varies by type
Duration Chronic
Types N/A
Causes Genetic factors, sun exposure, immunosuppression
Risks Family history, immunosuppression, UV exposure
Diagnosis Clinical examination, skin biopsy
Differential diagnosis Actinic keratosis, basal cell carcinoma, squamous cell carcinoma
Prevention N/A
Treatment Cryotherapy, laser therapy, topical medications
Medication 5-fluorouracil, imiquimod, retinoids
Prognosis N/A
Frequency Rare
Deaths N/A


File:Porokeratosis - high mag.jpg
Porokeratosis - high magnification
Microstructure of a steel powder particle

Porokeratosis is a group of rare, chronic, genetic disorders of keratinization characterized by atrophic patches surrounded by a distinctive hyperkeratotic ridge-like border called a cornoid lamella.

Types[edit]

There are several types of porokeratosis, including:

Symptoms[edit]

The symptoms of porokeratosis vary depending on the type, but may include:

  • Small, ring-like spots
  • Red, scaly patches
  • Itching or burning sensation
  • Painful cracks on the palms of the hands and soles of the feet

Causes[edit]

The exact cause of porokeratosis is unknown, but it is believed to be genetic. It may also be triggered by exposure to sunlight, immune system disorders, or skin injuries.

Diagnosis[edit]

Porokeratosis is diagnosed through a physical examination and a skin biopsy. The biopsy can reveal the characteristic cornoid lamella, which is a diagnostic feature of porokeratosis.

Treatment[edit]

Treatment for porokeratosis may include:

  • Topical creams and ointments
  • Cryotherapy
  • Laser therapy
  • Dermabrasion

Prognosis[edit]

The prognosis for porokeratosis varies depending on the type and severity of the condition. Some forms of porokeratosis may increase the risk of skin cancer.

See also[edit]

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