Prothioconazole
Prothioconazole is a broad-spectrum fungicide that is commonly used in agriculture to control a wide range of plant diseases. It belongs to the class of triazole fungicides and is known for its systemic action, which means it is absorbed by the plant and distributed throughout its tissues.
Chemical Structure and Properties[edit | edit source]
Prothioconazole has the chemical formula C14H15Cl2N3OS. It is a white crystalline solid with a slight odour. It is moderately soluble in water and has a low volatility. The compound is stable under normal storage conditions and is not expected to degrade in the environment.
Mode of Action[edit | edit source]
Prothioconazole works by inhibiting the biosynthesis of ergosterol, a critical component of fungal cell membranes. This disruption in ergosterol production leads to changes in membrane permeability and function, ultimately causing the death of the fungus.
Uses[edit | edit source]
Prothioconazole is used to control a variety of fungal diseases in a wide range of crops, including wheat, barley, rye, oats, and corn. It is effective against diseases such as rust, powdery mildew, and septoria leaf spot. It is often used in combination with other fungicides to increase efficacy and prevent the development of resistance.
Safety and Environmental Impact[edit | edit source]
Prothioconazole is classified as a low-risk pesticide by the EPA. It is not expected to be harmful to humans when used according to label instructions. However, it is toxic to aquatic organisms and should not be allowed to enter water bodies.
In the environment, prothioconazole is moderately persistent and has a low potential for bioaccumulation. It is not expected to pose a significant risk to non-target organisms when used appropriately.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD