Secondary malignant neoplasm

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Secondary Malignant Neoplasm is a type of cancer that originates from a primary site of cancer and spreads to other parts of the body. This process is known as metastasis. Secondary malignant neoplasms are a significant concern in cancer treatment and management, as they often signify advanced disease and can complicate treatment strategies.

Definition[edit | edit source]

A Secondary Malignant Neoplasm is a cancerous growth that develops as a result of metastasis from a primary cancer site. Unlike primary cancers, which are classified based on the tissue or organ in which they originate, secondary malignant neoplasms are identified by the location to which they have spread. For example, if lung cancer spreads to the brain, the resulting secondary malignant neoplasm is referred to as a brain metastasis from lung cancer.

Causes[edit | edit source]

Secondary malignant neoplasms occur when cancer cells break away from the primary tumor, travel through the bloodstream or lymphatic system, and form new tumors in other parts of the body. This process is influenced by various factors, including the type and stage of the primary cancer, the body's immune response, and the microenvironment of the metastatic site.

Diagnosis[edit | edit source]

The diagnosis of secondary malignant neoplasms often involves imaging tests such as CT scans, MRI, and PET scans. Biopsies may also be performed to confirm the diagnosis and determine the origin of the metastatic cells.

Treatment[edit | edit source]

The treatment of secondary malignant neoplasms depends on the location and extent of the metastasis, the patient's overall health, and the type and stage of the primary cancer. Treatment options may include surgery, radiation therapy, chemotherapy, immunotherapy, or a combination of these. In some cases, palliative care may be the primary focus to manage symptoms and improve quality of life.

Prognosis[edit | edit source]

The prognosis for patients with secondary malignant neoplasms varies widely and depends on several factors, including the type and stage of the primary cancer, the number and location of metastases, and the patient's overall health and response to treatment.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD