SiRNA-expressing SV40 vector
A simian virus 40 (SV40)-based shuttle vector, encoding small interfering RNA (siRNA), with potential antineoplastic activity.
Mechanism of action of SiRNA-expressing SV40 vector
The expression of siRNA in target tumor cells transfected with an siRNA-expressing SV40 vector may result in siRNA-mediated silencing of target oncogenes and, so, the inhibition of tumor cell growth and the induction of tumor cell death.
Clinical trials
Check for ACTIVE CLINICAL TRIALS
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Contributors: Prab R. Tumpati, MD
