Giant virus
A gigantic virus is a virus that is significantly larger in size compared to the majority of viruses. Giant viruses typically measure at least 0.5 micrometers in length. These viruses are distinguished from other types of viruses due to their one-of-a-kind architecture and genetic make-up, both of which can be found in their genomes.
Mimivirus[edit | edit source]
The Mimivirus, which was discovered in 1992 by researchers at the Institute Pasteur in France, is currently considered to be one of the most well-known large viruses. One of the viruses with the longest known length is the Mimivirus, which has DNA that is double-stranded and measures 0.75 micrometers in length, making it one of the largest known viruses. At first, researchers believed that it was a bacterium; however, additional investigation revealed that it was actually a virus that infected amoeba. This discovery was noteworthy because it enlarged the known size range and genetic complexity of viruses, and it challenged the traditional definition of a virus as a small infectious agent. Viruses have always been thought of as being relatively simple infectious agents.
Pandoravirus[edit | edit source]
Pandoravirus is yet another well-known example of a huge virus. It was first identified in 2013 by scientists working at the Université Paris-Saclay in France. Pandoraviruses are considerably bigger than Mimiviruses, measuring 1 micrometer in length and carrying genomes that are two times as big as those of Mimiviruses. Mimiviruses are only 0.5 micrometers in length. In the beginning, scientists believed that the Pandoravirus was a bacterium because it infects amoeba just like the Mimivirus does.
Evolution[edit | edit source]
It is well known that giant viruses include a diverse collection of genetic material, which can include genes that are typically located in bacteria as well as eukaryotic organisms. This points to the possibility that large viruses were involved in the development of cellular life at some point. Giant viruses have been postulated by some researchers to have either been the progenitors of current cells or to have had a role in the development of eukaryotic cells. This hypothesis has been supported by other researchers.
Clinical applications[edit | edit source]
In addition to the one-of-a-kind structures and genetic make-up that they possess, it has been shown that enormous viruses are also capable of performing a diverse array of useful functions. Because it is capable of transporting significant quantities of genetic material into cells, for instance, the Mimivirus has been utilized as a tool in the field of gene therapy. In addition, the finding of large viruses has resulted in the creation of new approaches to the study of viruses as well as new tools for manipulating viruses.
Need more research[edit | edit source]
However, there is still a lot that scientists do not know about the ecology and variety of gigantic viruses, and this is a topic that is actively being researched. Studies have shown that giant viruses can be found in a variety of environments, such as freshwater and marine environments, and that they can infect a wide variety of hosts, such as amoeba, protozoa, and algae. This is evidenced by the fact that giant viruses can be found in both freshwater and marine environments.
Summary[edit | edit source]
A giant virus, sometimes referred to as a girus, is a very large virus, some of which are larger than typical bacteria. They have extremely large genomes compared to other viruses and contain many unique genes not found in life forms. All known giant viruses belong to the phylum Nucleocytoviricota. Their discovery has also led to fresh insights into the beginnings of cellular life and has the potential to have applications in disciplines such as gene therapy and research on viruses.
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Contributors: Prab R. Tumpati, MD