Signet ring cell carcinoma

Signet ring cell carcinoma (SRCC) is a rare form of cancer that primarily affects the stomach or gastric region, but can also occur in other parts of the body such as the breast, colon, prostate, bladder, pancreas, and lung. It is named for the resemblance of the cancer cells to signet rings when viewed under a microscope.

Overview[edit | edit source]

SRCC is characterized by cells that are filled with mucin, a type of protein. This causes the nucleus of the cell to be pushed to the periphery, giving it the appearance of a signet ring. The presence of these cells is a defining characteristic of this type of cancer.

Symptoms[edit | edit source]

The symptoms of SRCC can vary depending on the location of the cancer. In the case of gastric SRCC, symptoms may include abdominal pain, nausea, vomiting, and weight loss. If the cancer is located in the colon, symptoms may include constipation, diarrhea, and rectal bleeding.

Diagnosis[edit | edit source]

Diagnosis of SRCC typically involves a combination of physical examination, medical history, and imaging tests. A biopsy may also be performed to confirm the diagnosis. The biopsy sample is examined under a microscope to look for the presence of signet ring cells.

Treatment[edit | edit source]

Treatment for SRCC depends on the stage of the cancer and the overall health of the patient. Options may include surgery, chemotherapy, and radiation therapy. In some cases, a combination of these treatments may be used.

Prognosis[edit | edit source]

The prognosis for SRCC is generally poor, as this type of cancer is often diagnosed at a late stage. However, early detection and treatment can improve the prognosis.

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