Acetanisole

From WikiMD's Food, Medicine & Wellness Encyclopedia

Acetanisol Synthesis.svg

Acetanisole is an organic compound with the chemical formula C9H10O2. It is classified as an ester, specifically formed from the reaction of acetic acid and anisole. Acetanisole is known for its sweet, floral aroma, reminiscent of anise or almond, making it a valuable additive in the flavor and fragrance industries. This compound is also referred to by its systematic name, 1-(4-methoxyphenyl)ethanone.

Properties[edit | edit source]

Acetanisole appears as a white, crystalline solid at room temperature. It is moderately soluble in water but exhibits good solubility in organic solvents such as ethanol, diethyl ether, and benzene. The compound has a melting point ranging from 54 to 56°C and a boiling point of approximately 258°C.

Synthesis[edit | edit source]

The synthesis of acetanisole involves the acetylation of anisole. This process typically uses acetyl chloride or acetic anhydride as the acetylating agent, with the reaction facilitated by a Lewis acid catalyst such as aluminium chloride (AlCl3).

Applications[edit | edit source]

Acetanisole's primary use is in the flavor and fragrance industry, where it is added to a variety of products to impart a sweet, floral scent and taste. It is commonly found in perfumes, soaps, air fresheners, and certain food products. Due to its pleasant aroma, acetanisole is also used in the formulation of various cosmetic products.

Safety[edit | edit source]

While acetanisole is generally considered safe for use in consumer products, it should be handled with care in its pure form. Direct contact with the skin or eyes may cause irritation, and inhalation of its dust can lead to respiratory discomfort. It is advisable to use appropriate personal protective equipment (PPE) when handling chemicals like acetanisole in a laboratory or industrial setting.

Environmental Impact[edit | edit source]

There is limited information on the environmental impact of acetanisole. However, as with many organic compounds, it is recommended to prevent its release into the environment to avoid potential harm to aquatic and terrestrial life.

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Contributors: Prab R. Tumpati, MD