Spindle cell lipoma

Spindle cell lipoma is a rare type of lipoma, a benign tumor composed of adipose tissue. It is characterized by a mixture of mature adipocytes and spindle cells. It was first described by Enzinger and Harvey in 1975.

Clinical Presentation

Spindle cell lipomas typically present as slow-growing, painless masses. They are most commonly found in the subcutaneous tissue of the back, neck, and shoulders of middle-aged to elderly men.

Pathology

Histologically, spindle cell lipomas are composed of a mixture of mature adipocytes and spindle cells. The spindle cells are arranged in short fascicles and have a uniform appearance. They are positive for CD34, a marker of vascular endothelial cells, and negative for S100, a marker of adipocytes and neural cells.

Treatment

The treatment of choice for spindle cell lipomas is surgical excision. Recurrence is rare after complete excision.

See Also

• Lipoma
• Adipose tissue
• CD34
• S100 protein

Spindle cell lipoma Resources
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