Sulprostone

Sulprostone is a synthetic prostaglandin analogue that is primarily used in the field of obstetrics and gynecology. It is a potent and selective prostaglandin E2 (PGE2) receptor agonist.

Pharmacology

Sulprostone is a prostaglandin E2 analogue. It has strong agonistic actions on the EP3 receptor, a subtype of prostaglandin E2 receptor. This receptor is involved in the contraction of smooth muscle, including the uterus. Therefore, sulprostone can induce uterine contractions.

Medical uses

Sulprostone is used in obstetrics and gynecology for the termination of pregnancy, induction of labor, and treatment of severe postpartum hemorrhage. It can also be used to treat gastric ulcers.

Side effects

The most common side effects of sulprostone include abdominal pain, nausea, vomiting, and diarrhea. In rare cases, it can cause severe allergic reactions.

See also

• Prostaglandin E2
• EP3 receptor
• Obstetrics
• Gynecology

Sulprostone Resources
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