Suprofen

Suprofen is a nonsteroidal anti-inflammatory drug (NSAID) that was developed by Janssen Pharmaceutica. It is primarily used in the treatment of pain and inflammation associated with conditions such as arthritis and gout.

Pharmacology

Suprofen is a member of the arylpropionic acid class of NSAIDs. It works by inhibiting the body's production of prostaglandins, chemicals that cause inflammation and pain. Suprofen is a non-selective cyclooxygenase inhibitor, meaning it blocks both COX-1 and COX-2 enzymes. This results in decreased production of prostaglandins, thereby reducing inflammation and pain.

Medical uses

Suprofen is used to relieve pain and inflammation caused by a variety of conditions, including rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It can also be used to treat acute gout attacks and other types of pain, such as dysmenorrhea (painful menstruation).

Side effects

Like other NSAIDs, Suprofen can cause a range of side effects. These can include gastrointestinal problems such as stomach ulcers and bleeding, kidney problems, and an increased risk of heart attack or stroke. It can also cause allergic reactions in some people.

History

Suprofen was developed by Janssen Pharmaceutica, a Belgian pharmaceutical company, in the 1970s. It was initially marketed under the brand name Profenal. However, it was withdrawn from the market in many countries due to concerns about its safety profile.

See also

• Nonsteroidal anti-inflammatory drug
• Arylpropionic acid
• Cyclooxygenase
• Prostaglandin

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