Testosterone phenylpropionate

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Chemical structure of Testosterone Phenylpropionate.

Testosterone phenylpropionate is a synthetic testosterone ester and a medication used in hormone replacement therapy (HRT) and for the treatment of various testosterone-related conditions. It is classified as an androgen and an anabolic steroid.

Chemical Properties[edit | edit source]

Testosterone phenylpropionate is a synthetic compound with chemical formula C28H36O3. It is derived from testosterone by the addition of a phenylpropionate ester group.

Medical Uses[edit | edit source]

Testosterone phenylpropionate is used medically for the following purposes:

  • Hormone Replacement Therapy (HRT): It is prescribed to individuals with testosterone deficiency to supplement testosterone levels and alleviate associated symptoms such as fatigue, low libido, and mood changes.
  • Treatment of Hypogonadism: Testosterone phenylpropionate is used in the management of hypogonadism, a condition where the testes do not produce enough testosterone.
  • Supportive Care in Certain Illnesses: In some medical conditions like cancer, it may be used to support muscle growth and overall well-being.

Administration[edit | edit source]

Testosterone phenylpropionate is typically administered via intramuscular injection. The frequency and dosage of injections are determined by a healthcare professional based on the individual's needs and medical condition.

Safety and Regulation[edit | edit source]

The use of testosterone phenylpropionate in hormone replacement therapy is regulated and should be prescribed and monitored by healthcare professionals. It may have side effects and should be used with caution, particularly in cases of testosterone abuse.

Research and Studies[edit | edit source]

Research on testosterone phenylpropionate continues to explore its effectiveness in hormone replacement therapy, its safety profile, and its role in improving the quality of life for individuals with testosterone deficiency.

Summary[edit | edit source]

Testosterone phenylpropionate (BAN; TPP) (brand name Testolent), or testosterone phenpropionate, also known as testosterone hydrocinnamate, is a synthetic anabolic-androgenic steroid (AAS) and an androgen ester. It was first synthesized in 1951 and was first described in the literature by 1953. The medication was an ingredient of several isolated AAS commercial products, but was never widely used. Testosterone phenylpropionate was also notably a component of Sustanon and Omnadren, as well as of Estandron Prolongatum, Lynandron Prolongatum, and Mixogen.

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Contributors: Prab R. Tumpati, MD