Toxic encephalopathy
Thioxanthene is a chemical compound that belongs to the class of organic compounds known as thioxanthenes. These are polycyclic aromatic compounds containing a thioxanthene moiety, which is a tricyclic compound made up of two benzene rings linearly fused to a cyclohexene ring, and carries a sulfur atom at the 10-position.
Chemical Structure[edit | edit source]
The chemical structure of thioxanthene is characterized by a system of three fused rings, two of which are aromatic (benzene rings) and one of which is a six-membered unsaturated ring (cyclohexene ring). The sulfur atom is located at the 10-position of the tricyclic system.
Uses[edit | edit source]
Thioxanthenes are used in the production of certain types of antipsychotic medications, such as chlorprothixene and flupenthixol. These medications are used to treat symptoms of schizophrenia and other types of mental disorders.
Pharmacology[edit | edit source]
Thioxanthene-based antipsychotics work by blocking the action of dopamine, a neurotransmitter in the brain. This helps to balance the chemical activity in the brain and reduce symptoms of mental disorders.
Side Effects[edit | edit source]
Like all medications, thioxanthene-based antipsychotics can cause side effects. These may include drowsiness, dry mouth, blurred vision, and constipation. In rare cases, they may cause serious side effects such as tardive dyskinesia, a condition characterized by involuntary movements of the face and body.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD