Trichoadenoma

A rare benign skin tumor

Overview

Histological image of Trichoadenoma of Nikolowski

Trichoadenoma, also known as Trichoadenoma of Nikolowski, is a rare benign skin tumor that originates from the hair follicles. It was first described by Nikolowski in 1958. This tumor is characterized by its well-circumscribed nodular appearance and is typically found on the face or scalp.

Histopathology

Trichoadenoma is histologically distinct, presenting as a well-defined dermal nodule. It is composed of multiple small cystic structures lined by stratified squamous epithelium. These cysts are filled with keratinous material. The surrounding stroma is usually fibrous and may contain scattered melanocytes.

Clinical Presentation

Patients with trichoadenoma usually present with a solitary, slow-growing nodule. The lesion is typically asymptomatic and may vary in size. It is most commonly found in adults and has no predilection for gender.

Diagnosis

The diagnosis of trichoadenoma is primarily based on histological examination. A skin biopsy is performed to obtain a sample of the lesion, which is then analyzed under a microscope. The presence of characteristic cystic structures and keratinous material confirms the diagnosis.

Treatment

Treatment of trichoadenoma is usually not necessary unless the lesion becomes symptomatic or for cosmetic reasons. Surgical excision is the treatment of choice and is curative. Recurrence after excision is rare.

Differential Diagnosis

The differential diagnosis for trichoadenoma includes other follicular tumors such as trichoepithelioma, pilomatricoma, and sebaceous adenoma. Accurate histopathological analysis is essential to distinguish trichoadenoma from these other entities.

Prognosis

The prognosis for patients with trichoadenoma is excellent. It is a benign tumor with no potential for malignant transformation. Once excised, it does not typically recur.

Related pages

• Trichoepithelioma
• Pilomatricoma
• Sebaceous adenoma
• Skin tumor