Trichoblastic fibroma

From WikiMD's Food, Medicine & Wellness Encyclopedia

Trichoblastic fibroma is a rare, benign tumor that originates from the hair follicle. It is a type of cutaneous condition that is characterized by the proliferation of trichoblasts, which are the cells responsible for the development of hair follicles.

History[edit | edit source]

The term "trichoblastic fibroma" was first introduced by the dermatologist A. Bernard Ackerman in 1982. Ackerman described the tumor as a benign proliferation of trichoblasts, which are the primitive cells that give rise to the hair follicle.

Clinical Presentation[edit | edit source]

Trichoblastic fibromas typically present as solitary, slow-growing, skin-colored nodules. They can occur anywhere on the body, but are most commonly found on the face, scalp, and neck. The size of the tumor can vary, but it is usually less than 2 cm in diameter.

Diagnosis[edit | edit source]

The diagnosis of trichoblastic fibroma is typically made through a combination of clinical examination and histopathology. The histopathological features of trichoblastic fibroma include a well-circumscribed dermal tumor composed of small, basaloid cells with scant cytoplasm. The tumor cells are arranged in nests and cords, and are often associated with a fibrous stroma.

Treatment[edit | edit source]

The treatment of choice for trichoblastic fibroma is surgical excision. The prognosis is excellent, as these tumors are benign and do not metastasize. However, recurrence may occur if the tumor is not completely excised.

See Also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD