Triclofos
Triclofos is a sedative and hypnotic medication primarily used for the short-term treatment of insomnia. It is a derivative of chloral hydrate and is known for its effectiveness in inducing sleep. Triclofos is often administered in the form of its sodium salt, triclofos sodium.
Pharmacology[edit | edit source]
Triclofos works by depressing the central nervous system (CNS), leading to sedation and sleep. It is metabolized in the body to trichloroethanol, which is the active metabolite responsible for its sedative effects. The drug has a relatively rapid onset of action and a moderate duration of effect, making it suitable for use as a sleep aid.
Medical Uses[edit | edit source]
Triclofos is primarily prescribed for the short-term management of insomnia, particularly in cases where other treatments have failed or are not suitable. It may also be used in certain medical procedures to induce sedation.
Side Effects[edit | edit source]
Common side effects of triclofos include:
In rare cases, more severe side effects can occur, such as:
Contraindications[edit | edit source]
Triclofos should not be used in individuals with a known hypersensitivity to the drug or its components. It is also contraindicated in patients with severe liver disease, kidney disease, or respiratory disorders.
Interactions[edit | edit source]
Triclofos can interact with other CNS depressants, such as alcohol, benzodiazepines, and opioids, leading to enhanced sedative effects. It is important to inform healthcare providers of all medications being taken to avoid potential interactions.
Dosage and Administration[edit | edit source]
The dosage of triclofos varies depending on the patient's age, weight, and medical condition. It is typically administered orally in liquid form. The exact dosage should be determined by a healthcare professional.
History[edit | edit source]
Triclofos was developed as an alternative to chloral hydrate, offering similar sedative properties with potentially fewer side effects. It has been used in clinical practice for several decades.
See Also[edit | edit source]
References[edit | edit source]
External Links[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
