Zapizolam

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Zapizolam is a pyridodiazepine drug, which is a benzodiazepine analog. It has anxiolytic effects and was sold for the treatment of insomnia.

Pharmacology[edit | edit source]

Zapizolam is a benzodiazepine receptor agonist. It has similar effects to other benzodiazepines, but with a slightly different mechanism of action. It has anxiolytic, anticonvulsant, hypnotic, sedative, skeletal muscle relaxant, and amnestic properties.

History[edit | edit source]

Zapizolam was patented in 1975 and came into medical use in 1981. It was marketed by the pharmaceutical company Upjohn (now part of Pfizer) under the trade name Dormalon. However, it was withdrawn from the market in the 1990s due to concerns about its potential for abuse and addiction.

Side effects[edit | edit source]

Like other benzodiazepines, zapizolam can cause a range of side effects, including drowsiness, dizziness, confusion, and impaired coordination. It can also cause physical dependence and withdrawal symptoms if used for a long period of time.

See also[edit | edit source]

References[edit | edit source]


Zapizolam Resources
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Contributors: Prab R. Tumpati, MD