2,5-Dimethoxy-4-amylamphetamine

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2,5-Dimethoxy-4-amylamphetamine (DOAM) is a psychedelic drug and a member of the DOx family of compounds which are known for their high potency, long duration, and mixture of psychedelic and stimulant effects.

Chemistry[edit | edit source]

2,5-Dimethoxy-4-amylamphetamine is a substituted amphetamine featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain. DOAM contains two methoxy functional groups CH3O- which are attached to carbons R2 and R5 as well as an amyl chain bound to carbon R4 of the phenyl ring.

Pharmacology[edit | edit source]

The mechanism that produces the hallucinogenic and entheogenic effects of DOAM is most likely to result from action as a 5-HT2A receptor agonist in the brain, a mechanism of action shared by various hallucinogenic drugs such as LSD and psilocin.

Effects[edit | edit source]

The effects of DOAM are reported to be extremely strong and long-lasting. Users report intense visuals, increased energy, and altered thought processes. The effects can last up to 24 hours, with the peak usually occurring in the first few hours.

Risks[edit | edit source]

As with all psychedelic substances, the use of DOAM carries the risk of triggering a psychotic or manic episode in susceptible individuals. It is also possible to experience a bad trip, which can be extremely distressing and psychologically damaging.

Legal Status[edit | edit source]

The legal status of DOAM varies by country, but it is generally considered a controlled substance under the United Nations Convention on Psychotropic Substances.

See Also[edit | edit source]



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