4-Hydroxytestosterone

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A synthetic anabolic-androgenic steroid

4-Hydroxytestosterone

4-Hydroxytestosterone

4-Hydroxytestosterone



Chemical nomenclature
IUPAC name (8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15-decahydrocyclopenta[a]phenanthren-3-one


























4-Hydroxytestosterone is a synthetic anabolic-androgenic steroid (AAS) that is derived from testosterone. It is known for its potential use in bodybuilding and athletic performance enhancement.

Chemical structure and properties[edit]

4-Hydroxytestosterone is a hydroxylated derivative of testosterone, specifically hydroxylated at the 4-position. This modification alters its pharmacokinetics and pharmacodynamics, potentially affecting its androgenic and anabolic activity.

Mechanism of action[edit]

As an AAS, 4-Hydroxytestosterone binds to androgen receptors in various tissues, promoting protein synthesis and muscle growth. Its hydroxyl group may influence its interaction with enzymes such as aromatase, potentially reducing its conversion to estrogens.

Uses[edit]

4-Hydroxytestosterone has been explored for its potential in enhancing muscle mass and strength. However, its use is not approved for medical purposes and is often associated with doping in sports.

Side effects[edit]

The use of 4-Hydroxytestosterone can lead to side effects typical of AAS, including acne, hair loss, and liver toxicity. Its impact on the endocrine system can also result in hormonal imbalances.

Legal status[edit]

4-Hydroxytestosterone is classified as a controlled substance in many countries due to its potential for abuse and health risks. It is banned by most sports organizations.

Related pages[edit]

Gallery[edit]

  • Chemical structure of 4-Hydroxytestosterone
    Chemical structure of 4-Hydroxytestosterone
  • 3D model of 4-Hydroxytestosterone
    3D model of 4-Hydroxytestosterone

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