5α-Dihydronorethandrolone
5α-Dihydronorethandrolone is a steroid and androgen that is derived from nandrolone. It is more commonly known as a metabolite of the anabolic steroid ethylestrenol (Maxibolin), and is believed to be formed in the body after the intake of ethylestrenol.
Chemical Structure[edit | edit source]
5α-Dihydronorethandrolone is a 17α-ethyl derivative of 19-nortestosterone. The chemical structure of 5α-Dihydronorethandrolone is similar to that of nandrolone, but with an additional hydrogen atom at the 5α position.
Pharmacology[edit | edit source]
As an androgen, 5α-Dihydronorethandrolone binds to and activates the androgen receptor (AR), which leads to changes in gene expression and increased protein synthesis. This can result in a variety of effects, including increased muscle mass and strength, and improved bone density.
Medical Uses[edit | edit source]
While 5α-Dihydronorethandrolone itself is not used in medicine, its parent compound, ethylestrenol, has been used for a variety of medical purposes. These include the treatment of osteoporosis, anemia, and certain forms of neoplasia.
Side Effects[edit | edit source]
The side effects of 5α-Dihydronorethandrolone are similar to those of other androgens and can include acne, hair loss, and gynecomastia. Long-term use can also lead to cardiovascular disease and liver damage.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD