5-HT1D

5-HT1D is a subtype of the 5-HT receptor that binds to the neurotransmitter serotonin. It is a G protein-coupled receptor (GPCR) that is coupled to Gi/Go and inhibits the release of neurotransmitters. The 5-HT1D receptor is found in the central nervous system (CNS), particularly in the basal ganglia and the frontal cortex.

Function

The 5-HT1D receptor is involved in a variety of functions in the body. It plays a role in the regulation of serotonin release, which can affect mood and behavior. It is also involved in the regulation of blood pressure and heart rate, and can influence the release of other neurotransmitters such as dopamine and norepinephrine.

Clinical significance

The 5-HT1D receptor is a target for the treatment of migraines. Drugs that activate this receptor, such as triptans, can help to relieve the symptoms of migraines. In addition, the 5-HT1D receptor is also a potential target for the treatment of depression and anxiety disorders.

See also

• 5-HT receptor
• Serotonin
• Neurotransmitter
• G protein-coupled receptor
• Migraine
• Depression
• Anxiety

References

5-HT1D Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski