Alder's sign

From WikiMD's Wellness Encyclopedia

Alder's Sign is a clinical sign used in the field of medicine, specifically in cardiology. It is named after the physician who first described it, Dr. John Alder. The sign is used to diagnose certain heart diseases and conditions, particularly those related to the mitral valve of the heart.

Definition[edit | edit source]

Alder's Sign is defined as the presence of a loud, harsh murmur that can be heard over the heart during a physical examination. This murmur is typically heard best at the apex of the heart, and is often associated with mitral valve prolapse.

Clinical Significance[edit | edit source]

The presence of Alder's Sign can indicate a number of different heart conditions. Most commonly, it is associated with mitral valve prolapse, a condition in which the mitral valve of the heart does not close properly. This can lead to blood flowing backwards into the left atrium of the heart, a condition known as mitral regurgitation.

In addition to mitral valve prolapse, Alder's Sign can also be indicative of other heart conditions, such as mitral stenosis or mitral valve regurgitation. It can also be present in patients with rheumatic heart disease, a condition that can damage the heart valves.

Diagnosis[edit | edit source]

The diagnosis of Alder's Sign is typically made during a physical examination. The physician will listen to the patient's heart using a stethoscope, and if a loud, harsh murmur is heard, this may indicate the presence of Alder's Sign.

Further diagnostic tests may be required to confirm the diagnosis and to determine the underlying cause of the murmur. These may include an echocardiogram, which uses sound waves to create images of the heart, or a cardiac catheterization, which involves inserting a thin tube into a blood vessel and guiding it to the heart.

Treatment[edit | edit source]

The treatment for conditions associated with Alder's Sign will depend on the underlying cause of the murmur. In many cases, treatment may involve medication to manage symptoms or to treat the underlying condition. In some cases, surgery may be required to repair or replace the affected heart valve.


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Contributors: Prab R. Tumpati, MD