Alpha glucosidase inhibitor

Alpha-glucosidase inhibitors are a class of anti-diabetic drugs that are used to manage Type 2 diabetes. They work by slowing down the breakdown of complex carbohydrates into glucose, thereby reducing the impact of carbohydrates on blood sugar levels.

Mechanism of Action

Alpha-glucosidase is an enzyme found in the small intestine that breaks down complex carbohydrates into simple sugars. Alpha-glucosidase inhibitors work by blocking this enzyme, thereby slowing the digestion of carbohydrates. This results in a slower and lower rise in blood glucose levels following meals.

Uses

Alpha-glucosidase inhibitors are primarily used in the treatment of Type 2 diabetes. They are often used in combination with other anti-diabetic drugs to achieve optimal blood glucose control. They may also be used in patients with impaired glucose tolerance to prevent the progression to Type 2 diabetes.

Side Effects

The most common side effects of alpha-glucosidase inhibitors are gastrointestinal, including flatulence, diarrhea, and abdominal pain. These side effects are usually mild and decrease over time.

Examples

Examples of alpha-glucosidase inhibitors include Acarbose, Miglitol, and Voglibose.

See Also

• Anti-diabetic drug
• Type 2 diabetes
• Carbohydrate
• Glucose
• Small intestine