Bromperidol decanoate

Bromperidol decanoate

Bromperidol decanoate is a typical antipsychotic medication of the butyrophenone class, which is used in the treatment of schizophrenia. It is a long-acting decanoate ester form of bromperidol, a potent dopamine antagonist.

Pharmacology

Bromperidol decanoate acts primarily by blocking dopamine receptors, specifically the D2 receptor. This inhibits the normal function of dopamine, a neurotransmitter that is involved in reward, motivation, and other important functions. By blocking these receptors, bromperidol decanoate can reduce the symptoms of schizophrenia, such as hallucinations and delusions.

Clinical Use

Bromperidol decanoate is used in the treatment of chronic schizophrenia and other psychotic disorders. It is particularly useful in patients who have difficulty adhering to a regular medication schedule, as the decanoate form of the drug allows for less frequent dosing.

Side Effects

Like other typical antipsychotics, bromperidol decanoate can cause a range of side effects. These can include extrapyramidal symptoms such as tremors and rigidity, tardive dyskinesia, and neuroleptic malignant syndrome. It can also cause sedation, weight gain, and sexual dysfunction.

See Also

• Antipsychotic
• Schizophrenia
• Dopamine antagonist