Calu-3

From WikiMD's Wellness Encyclopedia

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Calu-3 is a human lung cancer cell line that is commonly used in scientific research. It was derived from a pleural effusion of a patient with adenocarcinoma of the lung. Calu-3 cells are known for their ability to form tight junctions and polarize, making them a valuable model for studying airway epithelium and drug transport.

Characteristics[edit | edit source]

Calu-3 cells exhibit several key characteristics that make them useful for research:

Applications in Research[edit | edit source]

Calu-3 cells are widely used in various fields of research, including:

Culturing Calu-3 Cells[edit | edit source]

Calu-3 cells are typically cultured in Dulbecco's Modified Eagle Medium (DMEM) supplemented with fetal bovine serum (FBS). They require a humidified atmosphere with 5% carbon dioxide (CO2) at 37°C. Proper maintenance of these cells is crucial for ensuring their viability and functionality in experiments.

See Also[edit | edit source]

References[edit | edit source]

External Links[edit | edit source]

Contributors: Prab R. Tumpati, MD