Centre for Applied Genomics

Centre for Applied Genomics

The Centre for Applied Genomics (TCAG) is a research facility dedicated to the study of genomics and its applications in various fields such as medicine, agriculture, and biotechnology. It is located in Toronto, Ontario, Canada, and is affiliated with the Hospital for Sick Children (SickKids) and the University of Toronto.

History

The Centre for Applied Genomics was established in 1998 as a part of the Hospital for Sick Children. It was founded to provide researchers with access to advanced genomic technologies and expertise. Over the years, TCAG has grown to become one of the leading genomics research centers in the world.

Research Areas

TCAG focuses on several key areas of genomics research, including:

• Human genetics: Studying the genetic basis of human diseases and traits.
• Cancer genomics: Investigating the genetic changes that drive cancer development and progression.
• Neurogenomics: Exploring the genetic underpinnings of neurological and psychiatric disorders.
• Comparative genomics: Comparing the genomes of different species to understand evolutionary relationships and functional genomics.
• Functional genomics: Identifying the roles of genes and their interactions in biological processes.

Facilities and Technologies

The Centre for Applied Genomics is equipped with state-of-the-art facilities and technologies, including:

• Next-generation sequencing platforms
• Microarray technology
• Bioinformatics resources
• High-throughput screening systems
• CRISPR/Cas9 gene editing tools

Collaborations and Partnerships

TCAG collaborates with numerous national and international research institutions, universities, and industry partners. These collaborations aim to advance the understanding of genomics and its applications in various fields. Some of the notable partners include:

• Genome Canada
• Ontario Genomics
• Canadian Institutes of Health Research (CIHR)
• National Institutes of Health (NIH)

Education and Training

The Centre for Applied Genomics is committed to educating and training the next generation of scientists. It offers various programs, workshops, and seminars for students, researchers, and professionals in the field of genomics. These educational initiatives aim to enhance the skills and knowledge required to conduct cutting-edge genomics research.

Impact and Achievements

TCAG has made significant contributions to the field of genomics, including:

• Identifying genetic mutations associated with various diseases
• Developing new diagnostic tools and therapies
• Advancing the understanding of complex genetic traits
• Contributing to large-scale genomics projects such as the Human Genome Project and the 1000 Genomes Project

See Also

• Genomics
• Human Genome Project
• Next-generation sequencing
• Bioinformatics
• CRISPR