Centre for Arab Genomic Studies

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thumb for rationale Centre for Arab Genomic Studies (CAGS) is a scientific research organization based in the United Arab Emirates that focuses on the study of human genetics in the Arab population. Its primary goal is to understand the genetic disorders prevalent in the Arab world and to use this knowledge to prevent and manage these conditions more effectively. The Centre plays a pivotal role in facilitating research and collaboration in the field of genetic disorders, genomics, and biotechnology across the Arab nations.

Background[edit | edit source]

The Arab world has a high incidence of certain genetic disorders due to various factors, including high rates of consanguineous marriages (marriage between closely related individuals). This has led to an increased prevalence of autosomal recessive genetic disorders such as thalassemia, sickle cell anemia, and certain metabolic disorders. Recognizing the need for a comprehensive approach to tackle these challenges, the Centre for Arab Genomic Studies was established.

Mission[edit | edit source]

The mission of CAGS is to reduce the burden of genetic diseases in the Arab world through research, education, and public awareness. The Centre aims to:

  • Identify and catalog genetic disorders prevalent in the Arab population.
  • Support and conduct research in human genetics.
  • Promote public awareness about genetic disorders and their prevention.
  • Foster collaboration among scientists, researchers, and healthcare professionals across the Arab world.

Research and Activities[edit | edit source]

CAGS undertakes a variety of activities to achieve its objectives, including:

  • Maintaining a database of genetic disorders known to affect the Arab population, known as the Catalogue of Transmission Genetics in Arabs (CTGA) database. This resource is invaluable for researchers and healthcare professionals.
  • Organizing conferences, workshops, and seminars to disseminate knowledge and foster collaboration among stakeholders in the field of genetics.
  • Publishing research findings and reports on genetic diseases prevalent in the Arab world.

Impact[edit | edit source]

The work of CAGS has significantly contributed to the understanding of genetic disorders in the Arab population. By cataloging genetic diseases and mutations, the Centre has provided a foundation for genetic research and healthcare planning in the region. Its efforts in public education and awareness have also contributed to a greater understanding of genetic disorders and their prevention among the general public.

Challenges[edit | edit source]

Despite its achievements, CAGS faces several challenges, including limited funding for genetic research, the need for more comprehensive genetic screening programs, and the task of overcoming cultural and social barriers to genetic counseling and testing in some communities.

Future Directions[edit | edit source]

Looking forward, CAGS aims to expand its research activities, improve genetic healthcare services, and enhance public awareness programs across the Arab world. The Centre also seeks to strengthen international collaborations to advance the field of genomics and genetic disorder management globally.

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Contributors: Prab R. Tumpati, MD