Cutaneous perforating disorders

Cutaneous perforating disorders are a group of skin conditions characterized by the transepidermal elimination of dermal material. The disorders are classified into four main types: Kyrle disease, Reactive perforating collagenosis, Elastosis perforans serpiginosa, and Perforating folliculitis.

Classification

Cutaneous perforating disorders are classified into four main types:

• Kyrle disease - This is a rare, acquired, perforating dermatosis that is characterized by hyperkeratotic papules and nodules, which are often located on the lower extremities.

• Reactive perforating collagenosis - This is a rare form of transepidermal elimination in which altered collagen is extruded through the epidermis. It can occur in both inherited and acquired forms.

• Elastosis perforans serpiginosa - This is a rare skin disorder where connective tissue and elastic tissue is viewed as foreign material and is eliminated from the body through the skin.

• Perforating folliculitis - This is a condition characterized by the transepidermal elimination of keratin through the hair follicles.

Symptoms

The symptoms of cutaneous perforating disorders vary depending on the specific type of disorder. However, common symptoms include skin lesions, itching, and in some cases, a secondary infection due to scratching or picking at the lesions.

Causes

The exact cause of cutaneous perforating disorders is unknown. However, they are often associated with systemic diseases such as diabetes mellitus, chronic kidney disease, and liver disease. Some forms of the disorder are also thought to be genetic.

Treatment

Treatment for cutaneous perforating disorders typically involves managing the symptoms and any underlying conditions. This may include the use of topical creams, oral medications, and in some cases, light therapy.

See also

• Dermatology
• Skin disease
• Transepidermal elimination