Dementia familial British
Alternate names
FBD; Cerebral amyloid angiopathy, British type; Presenile dementia with spastic ataxia; Familial British dementia; Familial dementia, British type
Definition
A rare, neurodegenerative disease characterized by progressive cognitive impairment, spastic tetraparesis, and cerebellar ataxia resulting from amyloid deposits in the brain. Spasticity with increased deep tendon reflexes and tone are early symptoms, muscular rigidity evolves later. Progressive mental deterioration usually starts with apathy and impaired memory with progression to complete disorientation.
NIH genetic and rare disease info
Dementia familial British is a rare disease.
Resources
Frequently asked questions
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Contributors: Prab R. Tumpati, MD
