Elastosis perforans serpiginosa
(Redirected from EPS)
Editor-In-Chief: Prab R Tumpati, MD
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| Elastosis perforans serpiginosa | |
|---|---|
Error creating thumbnail: Elastosis perforans serpiginosa | |
| Synonyms | EPS |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Papules, hyperkeratosis, pruritus |
| Complications | Scarring |
| Onset | Typically in adolescence or early adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown, associated with genetic disorders |
| Risks | Down syndrome, Ehlers-Danlos syndrome, Marfan syndrome |
| Diagnosis | Clinical diagnosis, skin biopsy |
| Differential diagnosis | Kyrle disease, reactive perforating collagenosis, perforating folliculitis |
| Prevention | N/A |
| Treatment | Topical retinoids, cryotherapy, laser therapy |
| Medication | N/A |
| Prognosis | Variable, often chronic |
| Frequency | Rare |
| Deaths | N/A |
Elastosis perforans serpiginosa (EPS) is a rare skin condition characterized by the elimination of abnormal elastic fibers through the skin. It is classified as a primary perforating dermatosis. That is, a condition where there is transepidermal elimination of dermal material. The condition is often associated with D-penicillamine therapy, Down syndrome, and Ehlers-Danlos syndrome.
Etiology[edit | edit source]
The exact cause of EPS is unknown. However, it is often associated with certain conditions and medications. These include:
Symptoms[edit | edit source]
The symptoms of EPS include:
- Red or skin-colored bumps
- Lesions that form a winding pattern
- Itching
Diagnosis[edit | edit source]
Diagnosis of EPS is primarily based on the clinical appearance of the skin lesions. A skin biopsy may be performed to confirm the diagnosis.
Treatment[edit | edit source]
Treatment options for EPS include:
- Topical retinoids
- Cryotherapy
- Laser therapy
Elastosis_perforans_serpiginosa images[edit | edit source]
Histopathology of elastosis perforans serpiginosa
Autosomal dominant inheritance pattern
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
