Epithelial-myoepithelial carcinoma

From WikiMD's Wellnesspedia

Epithelial-myoepithelial carcinoma (EMCa) is a rare malignant tumour that typically arises in a salivary gland and consists of both an epithelial and myoepithelial component. They are predominantly found in the parotid gland[1] and represent approximately 1% of salivary gland tumours.[2]

Cause[edit | edit source]

Diagnosis[edit | edit source]

EMCas are diagnosed by examination of tissue, e.g. a biopsy.

This tumour is characterised by biphasic tubular structures composed of inner ductal and outer clear myoepithelial cells.

Its appearance is very similar to adenomyoepithelioma of the breast, which may be the same tumour at a different anatomical site.[3]

The histologic differential diagnosis includes adenoid cystic carcinoma and pleomorphic adenoma.

Prognosis[edit | edit source]

They generally have a good prognosis.[1] In one larger study, the 5-year and 10-year survival were over 90% and 80% respectively.[4]

See also[edit | edit source]

References[edit | edit source]

  1. 1.0 1.1


Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD