Erythroblastosis fetalis
Erythroblastosis fetalis is a severe medical condition that most commonly occurs in a fetus due to incompatibility between the blood types of the mother and the fetus. This condition is also known as hemolytic disease of the newborn (HDN) or Rh disease.
Causes[edit | edit source]
Erythroblastosis fetalis is caused by an incompatibility between the blood types of the mother and the fetus. This incompatibility can occur if the mother has Rh-negative blood and the fetus has Rh-positive blood, a condition known as Rh incompatibility. The mother's immune system can produce antibodies against the Rh-positive blood cells of the fetus, leading to hemolysis, or destruction of the fetus's red blood cells.
Symptoms[edit | edit source]
Symptoms of erythroblastosis fetalis can vary depending on the severity of the condition. They may include:
- Jaundice
- Anemia
- Heart failure
- Edema (swelling)
- Hepatosplenomegaly (enlargement of the liver and spleen)
Diagnosis[edit | edit source]
Diagnosis of erythroblastosis fetalis can be made through various tests, including:
Treatment[edit | edit source]
Treatment for erythroblastosis fetalis may include:
Prevention[edit | edit source]
Prevention of erythroblastosis fetalis is possible through the administration of Rh immune globulin to the mother during pregnancy and after delivery.
See also[edit | edit source]
References[edit | edit source]
Erythroblastosis fetalis Resources | |
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Contributors: Prab R. Tumpati, MD