Estradiol/estrone/estriol
Overview of Estradiol, Estrone, and Estriol
Estradiol, Estrone, Estriol
{{This hormone-related article is a stub.}}
Estradiol, Estrone, and Estriol are the three main types of estrogen hormones found in the human body. These hormones play crucial roles in the development and regulation of the female reproductive system and secondary sexual characteristics.
Estradiol[edit | edit source]
Estradiol (E2) is the most potent and prevalent form of estrogen in premenopausal women. It is primarily produced by the ovaries, but also in smaller amounts by the adrenal glands and placenta. Estradiol is essential for the regulation of the menstrual cycle and is involved in the development of breast tissue, uterine lining, and bone density.
Functions[edit | edit source]
Estradiol is involved in:
- Regulation of the menstrual cycle
- Development of female secondary sexual characteristics
- Maintenance of bone health
- Modulation of mood and cognitive function
Estrone[edit | edit source]
Estrone (E1) is a weaker form of estrogen and is the primary estrogen present in postmenopausal women. It is produced mainly in the adipose tissue and liver. Estrone can be converted into estradiol and vice versa, depending on the body's needs.
Functions[edit | edit source]
Estrone plays a role in:
- Maintaining bone density
- Supporting cardiovascular health
- Modulating metabolism
Estriol[edit | edit source]
Estriol (E3) is the weakest of the three estrogens and is primarily produced during pregnancy by the placenta. It is considered a marker of fetal health and well-being.
Functions[edit | edit source]
Estriol is involved in:
- Supporting the growth and development of the fetus
- Preparing the body for labor and delivery
- Modulating the immune system during pregnancy
Clinical Significance[edit | edit source]
The balance of estradiol, estrone, and estriol is crucial for female health. Imbalances can lead to conditions such as estrogen dominance, osteoporosis, and menstrual disorders.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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Contributors: Prab R. Tumpati, MD
