Glemanserin
Glemanserin is a pharmaceutical drug that belongs to the class of serotonin antagonist and reuptake inhibitor (SARI) medications. It is primarily used in the treatment of major depressive disorder (MDD) and anxiety disorders.
Pharmacology[edit | edit source]
Glemanserin works by inhibiting the reuptake of serotonin, a neurotransmitter that plays a key role in mood regulation. By blocking the reuptake of serotonin, Glemanserin increases the amount of this neurotransmitter available in the brain, which can help to alleviate the symptoms of depression and anxiety.
In addition to its serotonin reuptake inhibiting properties, Glemanserin also acts as an antagonist at certain serotonin receptors. This means that it blocks these receptors, preventing serotonin from binding to them and exerting its effects. This dual action on serotonin reuptake and receptor antagonism is what classifies Glemanserin as a SARI.
Clinical Use[edit | edit source]
Glemanserin is used in the treatment of major depressive disorder and anxiety disorders. It may be prescribed as a standalone treatment, or in combination with other medications, depending on the severity of the patient's symptoms and their response to treatment.
Side Effects[edit | edit source]
Like all medications, Glemanserin can cause side effects. These may include nausea, dizziness, dry mouth, and sleep disturbances. In rare cases, Glemanserin may cause more serious side effects, such as suicidal thoughts or behaviors. Patients should be closely monitored for any changes in mood or behavior while taking this medication.
See Also[edit | edit source]
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