Haemolytic anaemia

Haemolytic anaemia is a condition characterized by the premature destruction of red blood cells (RBCs) in the bloodstream, before their normal lifespan of 120 days is complete. This leads to a shortage of RBCs, causing anaemia.

Causes

Haemolytic anaemia can be caused by a variety of factors, including immune system disorders, infections, certain medications, blood diseases, and genetic disorders. It can also be caused by mechanical factors such as artificial heart valves.

Symptoms

The symptoms of haemolytic anaemia can vary depending on the severity of the condition. Common symptoms include fatigue, weakness, shortness of breath, and pale skin. More severe cases can lead to jaundice, dark urine, rapid heart rate, and enlarged spleen.

Diagnosis

Diagnosis of haemolytic anaemia typically involves a series of blood tests to check for anemia and to determine the cause of the condition. These tests may include a complete blood count (CBC), reticulocyte count, direct antiglobulin test (DAT), and others.

Treatment

Treatment for haemolytic anaemia depends on the underlying cause of the condition. It may involve treating the underlying disease, stopping or changing medications that are causing the condition, or in severe cases, blood transfusions or surgery to remove the spleen.

See also

• Anaemia
• Red blood cells
• Blood diseases
• Immune system

Haemolytic anaemia Resources
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