Histiocytosis
(Redirected from Histiocytoses)
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Histiocytosis | |
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Synonyms | N/A |
Pronounce | N/A |
Specialty | N/A |
Symptoms | Varies by type; may include fever, weight loss, skin rash, bone pain |
Complications | Organ dysfunction, bone lesions, diabetes insipidus |
Onset | Usually in childhood |
Duration | Varies |
Types | Langerhans cell histiocytosis, Hemophagocytic lymphohistiocytosis, Rosai-Dorfman disease |
Causes | Abnormal proliferation of histiocytes |
Risks | Genetic factors, immune system dysregulation |
Diagnosis | Biopsy, imaging studies, blood tests |
Differential diagnosis | Infection, malignancy, autoimmune disease |
Prevention | N/A |
Treatment | Chemotherapy, radiation therapy, immunotherapy, surgery |
Medication | N/A |
Prognosis | Varies by type and severity |
Frequency | Rare |
Deaths | N/A |
Histiocytosis is a general name for a group of syndromes that involve an abnormal increase in the number of immune cells known as histiocytes. The disease can affect anyone from infants to older adults.
Types of Histiocytosis[edit | edit source]
There are several types of histiocytosis, including:
- Langerhans cell histiocytosis (LCH): This is the most common type of histiocytosis. LCH can damage skin, bones, and other parts of the body, or form tumors.
- Non-Langerhans cell histiocytosis: This type includes a variety of conditions that cause histiocytes to build up in certain parts of the body, such as the skin, lymph nodes, and spleen.
- Hemophagocytic lymphohistiocytosis (HLH): This is a severe form of histiocytosis that can affect many organs throughout the body.
Symptoms[edit | edit source]
The symptoms of histiocytosis can vary greatly depending on the type and severity of the condition. They may include:
Diagnosis[edit | edit source]
Histiocytosis is diagnosed through a combination of medical history, physical examination, and laboratory tests. These may include:
Treatment[edit | edit source]
Treatment for histiocytosis depends on the type and severity of the condition. It may include:
Prognosis[edit | edit source]
The prognosis for individuals with histiocytosis varies greatly. Some people may recover completely with treatment, while others may experience long-term complications or disability.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD