Isopropyl acetate

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Isopropyl acetate


Isopropyl acetate is an organic compound with the chemical formula C5H10O2. It is a ester formed from the chemical reaction between acetic acid and isopropanol, a process known as esterification. Isopropyl acetate is commonly used as a solvent in the production of lacquers, inks, and other coatings, due to its fast evaporation rate and pleasant odor. It is also used in the pharmaceutical industry as a solvent or an extractant.

Properties[edit | edit source]

Isopropyl acetate is a colorless, flammable liquid with a fruity odor, which is reminiscent of pear drops. It is miscible with most organic solvents, including alcohols, ketones, and aliphatic hydrocarbons, but has limited solubility in water. The compound has a boiling point of approximately 88°C (190°F) and a melting point of -73°C (-99°F).

Production[edit | edit source]

The production of isopropyl acetate primarily involves the acid-catalyzed esterification of acetic acid with isopropanol. The reaction can be accelerated by the presence of a strong acid catalyst, such as sulfuric acid. The process yields isopropyl acetate and water as by-products. Following the reaction, isopropyl acetate is typically purified through distillation.

Uses[edit | edit source]

Isopropyl acetate's primary use is as a solvent in the manufacture of various products. Its fast evaporation rate makes it suitable for use in quick-drying lacquers and paints, as well as in the printing industry for printing inks. It is also used as a solvent in the pharmaceutical industry, where it is involved in the production of medicines and as an extractant in the preparation of natural products.

In addition to its industrial applications, isopropyl acetate is used in the formulation of cosmetics and personal care products, where it functions as a fragrance ingredient and solvent.

Safety and Environmental Impact[edit | edit source]

Isopropyl acetate is considered to be of low toxicity, but it can cause irritation to the skin, eyes, and respiratory system upon prolonged exposure. It is highly flammable and poses a fire risk if not handled properly. In terms of environmental impact, isopropyl acetate can contribute to photochemical smog formation if released into the atmosphere.

Proper safety measures, including adequate ventilation and the use of personal protective equipment (PPE), are recommended when handling isopropyl acetate to minimize exposure and reduce the risk of fire.

Regulation[edit | edit source]

Regulatory bodies, such as the Environmental Protection Agency (EPA) in the United States and the European Chemicals Agency (ECHA) in the European Union, have set guidelines and regulations for the use and disposal of isopropyl acetate to protect human health and the environment.

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Contributors: Prab R. Tumpati, MD