Ketorfanol

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Ketorfanol

Ketorfanol is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of pain and inflammation. It is a derivative of ketoprofen, and is often used in the management of arthritis, dysmenorrhea, and other conditions associated with pain and inflammation.

Pharmacology

Ketorfanol works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are chemicals in the body that cause pain and inflammation. By inhibiting COX, Ketorfanol reduces the levels of prostaglandins, thereby reducing pain and inflammation.

Clinical Use

Ketorfanol is used in the treatment of various conditions that cause pain and inflammation. These include:

• Arthritis: Ketorfanol is often used to manage the pain and inflammation associated with arthritis. It can be used in both osteoarthritis and rheumatoid arthritis.
• Dysmenorrhea: Ketorfanol can be used to manage the pain associated with menstrual cramps.
• Other Painful Conditions: Ketorfanol can also be used to manage pain and inflammation in other conditions, such as bursitis, tendonitis, and gout.

Side Effects

Like all NSAIDs, Ketorfanol can cause side effects. These can include gastrointestinal problems, such as stomach pain, ulcers, and bleeding. It can also cause kidney problems, liver problems, and an increased risk of heart attack and stroke. It is important for patients to discuss these risks with their healthcare provider before starting treatment with Ketorfanol.

See Also

• Non-steroidal anti-inflammatory drug
• Ketoprofen
• Cyclooxygenase
• Prostaglandins