Lymphangioleiomyomatosis

Lymphangioleiomyomatosis (LAM) is a rare lung disease that typically affects women of childbearing age. In LAM, muscle cells that line the lungs' airways and blood vessels begin to multiply abnormally. These LAM cells form clusters and can cause blockages, leading to a variety of symptoms.

Symptoms[edit | edit source]

The symptoms of LAM can vary greatly from person to person. Some people may have no symptoms at all, while others may experience:

Shortness of breath, especially during physical activity
Chest pain
Frequent cough, sometimes with blood (hemoptysis)
Fatigue
Wheezing

Causes[edit | edit source]

The exact cause of LAM is unknown. However, it is believed to be related to mutations in the TSC1 or TSC2 genes. These genes are involved in controlling cell growth, and mutations can lead to uncontrolled growth and division of cells.

Diagnosis[edit | edit source]

Diagnosis of LAM can be challenging, as its symptoms are similar to those of other lung diseases. However, certain tests can help in the diagnosis:

High-resolution computed tomography (HRCT) scan
Lung function test
Biopsy
Blood test

Treatment[edit | edit source]

There is currently no cure for LAM, but treatments can help manage symptoms and slow the progression of the disease. These may include:

Prognosis[edit | edit source]

The prognosis for individuals with LAM varies. Some people may remain stable for many years, while others may experience a rapid progression of the disease.

See also[edit | edit source]

Lymphangioleiomyomatosis Resources
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