Marginal zone lymphoma

Marginal zone lymphoma (MZL) is a type of Non-Hodgkin lymphoma that affects B cells. It is named for the marginal zone of the lymph node where these cells are found. MZL is a slow-growing, or indolent, lymphoma. There are three types of MZL: extranodal MZL of mucosa-associated lymphoid tissue (MALT), nodal MZL, and splenic MZL.

Types[edit | edit source]

Extranodal MZL of MALT[edit | edit source]

Extranodal marginal zone B cell lymphoma or MALT lymphoma, is the most common type of MZL. It can occur in various parts of the body, including the stomach, lungs, eyes, and skin.

Nodal MZL[edit | edit source]

Nodal marginal zone B cell lymphoma is a rare type of MZL that occurs in the lymph nodes.

Splenic MZL[edit | edit source]

Splenic marginal zone lymphoma affects the spleen and the blood. It can also affect the bone marrow.

Symptoms[edit | edit source]

Symptoms of MZL can vary depending on the type and location of the lymphoma. They may include swelling of the lymph nodes, stomach pain, fatigue, and weight loss.

Diagnosis[edit | edit source]

Diagnosis of MZL typically involves a biopsy of the affected tissue. Other tests may include blood tests, imaging tests, and a bone marrow biopsy.

Treatment[edit | edit source]

Treatment for MZL depends on the type and stage of the lymphoma, as well as the patient's overall health. Options may include watchful waiting, radiation therapy, chemotherapy, immunotherapy, and in some cases, surgery.

Prognosis[edit | edit source]

The prognosis for MZL is generally good, with many patients living for many years after diagnosis. However, the disease is often not curable and may require ongoing treatment.

See also[edit | edit source]

Marginal zone lymphoma Resources
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