N-Ethyltryptamine

N-Ethyltryptamine

N-Ethyltryptamine (NET), also known as ethyltryptamine, is a psychedelic, hallucinogenic, and entactogenic drug of the tryptamine class. It is an analog of tryptamine with an ethyl substituent at the amine nitrogen atom.

History

N-Ethyltryptamine was first synthesized in the early 1960s. It was initially studied for its potential therapeutic uses, particularly in the treatment of mood disorders and anxiety disorders. However, due to its potent psychedelic effects, its use in a clinical setting was largely discontinued by the end of the 1960s.

Pharmacology

N-Ethyltryptamine acts primarily as a serotonin receptor agonist. It has a high affinity for the 5-HT2A receptor, which is thought to be primarily responsible for its psychedelic effects. It also has a moderate affinity for the 5-HT1A and 5-HT2C receptors.

Effects

The effects of N-Ethyltryptamine are similar to those of other psychedelic tryptamines. These can include visual hallucinations, altered thought processes, and a heightened sense of empathy and emotional connectivity. The intensity and duration of these effects can vary widely depending on the dose and individual user's physiology.

Legal Status

The legal status of N-Ethyltryptamine varies by country. In the United States, it is classified as a Schedule I controlled substance under the Controlled Substances Act. This means it is illegal to manufacture, distribute, or possess without a license. In other countries, such as the United Kingdom, it is not specifically controlled but may fall under general restrictions on tryptamines.

See Also

• Tryptamine
• Psychedelic drug
• Hallucinogen
• Entactogen