Orf (disease)

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sheep_with_orf.jpg

Contagious pustular dermatitis in sheep and goats


Orf (disease)
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Orf, also known as contagious pustular dermatitis, scabby mouth, or contagious ecthyma, is a viral disease that primarily affects sheep and goats. It is caused by the Orf virus, a member of the Parapoxvirus genus. The disease is characterized by the formation of pustular lesions on the lips, muzzle, and in the mouth of affected animals.

Symptoms[edit | edit source]

The primary symptoms of orf include:

  • Lesions on the lips, muzzle, and in the mouth
  • Swelling and redness around the affected areas
  • Secondary bacterial infections may occur, leading to further complications

Transmission[edit | edit source]

Orf is highly contagious and can be transmitted through direct contact with infected animals or contaminated fomites. The virus can survive in the environment for extended periods, making it difficult to control outbreaks.

Diagnosis[edit | edit source]

Diagnosis of orf is typically based on clinical signs and symptoms. Laboratory tests, such as polymerase chain reaction (PCR) and virus isolation, can be used to confirm the presence of the orf virus.

Treatment[edit | edit source]

There is no specific antiviral treatment for orf. Supportive care, including the use of antibiotics to treat secondary bacterial infections, is the primary approach to managing the disease. In severe cases, animals may require additional supportive measures, such as fluid therapy.

Prevention[edit | edit source]

Preventive measures for orf include:

  • Maintaining good hygiene and biosecurity practices
  • Isolating infected animals to prevent the spread of the virus
  • Vaccination of susceptible animals, particularly in areas where the disease is endemic

Human Infection[edit | edit source]

Orf is a zoonotic disease, meaning it can be transmitted from animals to humans. Human infection typically occurs through direct contact with infected animals or contaminated materials. In humans, orf presents as a localized skin lesion, usually on the hands or fingers.

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Contributors: Prab R. Tumpati, MD