Ortho-DOT
Ortho-DOT is a chemical compound that belongs to the phenethylamine class of compounds. It is a psychedelic drug and a serotonin receptor agonist. The compound is known for its psychedelic effects, which are similar to those of other psychedelics such as LSD and psilocybin.
Chemistry[edit | edit source]
Ortho-DOT is a substituted phenethylamine, which is a large family of organic compounds. It is structurally related to other psychedelic phenethylamines such as 2C-B and DOB. The compound contains a phenethylamine core, which consists of a phenyl ring bound to an amino (NH2) group through an ethyl chain. Ortho-DOT also contains two oxygen atoms bound to the phenyl ring at the ortho position, hence the name Ortho-DOT.
Pharmacology[edit | edit source]
As a psychedelic, Ortho-DOT acts primarily as a serotonin receptor agonist. It binds to and activates the serotonin 2A receptor (5-HT2A receptor), which is thought to be primarily responsible for the psychedelic effects of the drug. The exact mechanism of action of Ortho-DOT is not fully understood, but it is thought to involve a complex interplay of various neurotransmitter systems, including the serotonin, dopamine, and norepinephrine systems.
Effects[edit | edit source]
The effects of Ortho-DOT are similar to those of other psychedelics. These can include hallucinations, altered perception of time and space, enhanced introspection, and emotional amplification. The intensity and duration of these effects can vary widely depending on the dose and individual physiology.
Legal Status[edit | edit source]
The legal status of Ortho-DOT varies by country. In many countries, it is a controlled substance, meaning its manufacture, distribution, and use are regulated by law. In some countries, it is completely illegal, while in others it may be legal for certain uses, such as research or therapeutic use.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD