Ovarian germ cell tumor

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Ovarian germ cell tumor is a type of tumor that originates from the egg-producing cells in the ovary. These tumors are rare and account for about 2% of all ovarian cancer cases. They are most commonly diagnosed in women under the age of 20, but can occur at any age.

Types[edit | edit source]

There are several types of ovarian germ cell tumors, including:

  • Dysgerminoma: This is the most common type of ovarian germ cell tumor. It is usually diagnosed at an early stage and has a high cure rate.
  • Yolk sac tumor: Also known as endodermal sinus tumor, this is a rare and aggressive type of ovarian germ cell tumor. It is most commonly diagnosed in children and young women.
  • Immature teratoma: This type of tumor contains cells that resemble those of an early embryo. It is usually diagnosed in young women and has a high cure rate if detected early.
  • Embryonal carcinoma: This is a very rare type of ovarian germ cell tumor. It is aggressive and often diagnosed at a late stage.

Symptoms[edit | edit source]

The symptoms of ovarian germ cell tumors can vary depending on the type and stage of the tumor. Common symptoms include:

Diagnosis[edit | edit source]

Ovarian germ cell tumors are diagnosed through a combination of physical examination, imaging tests, and biopsy. Blood tests may also be done to check for elevated levels of certain tumor markers, such as alpha-fetoprotein (AFP) and human chorionic gonadotropin (hCG).

Treatment[edit | edit source]

The treatment for ovarian germ cell tumors depends on the type and stage of the tumor. Treatment options include:

  • Surgery: This is the primary treatment for most ovarian germ cell tumors. The goal of surgery is to remove as much of the tumor as possible.
  • Chemotherapy: This is often used after surgery to kill any remaining cancer cells. It may also be used before surgery to shrink large tumors.
  • Radiation therapy: This is rarely used for ovarian germ cell tumors, but may be an option in certain cases.

Prognosis[edit | edit source]

The prognosis for ovarian germ cell tumors is generally good, especially if the tumor is diagnosed at an early stage. The overall 5-year survival rate for women with ovarian germ cell tumors is over 90%.

See also[edit | edit source]

Ovarian germ cell tumor Resources
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Contributors: Prab R. Tumpati, MD, Dr.T