Phillip D. Zamore

Phillip Zamore 2016 sq

Phillip D. Zamore is an American molecular biologist and geneticist known for his pioneering work in the field of RNA interference (RNAi). He is a professor at the University of Massachusetts Medical School and a co-director of the RNA Therapeutics Institute.

Early Life and Education

Phillip D. Zamore was born in New York City. He completed his undergraduate studies at Harvard University, where he received a Bachelor of Arts degree in biochemistry. He then pursued his Ph.D. in molecular biology at the Massachusetts Institute of Technology (MIT), where he worked under the supervision of David Bartel.

Career

After completing his Ph.D., Zamore conducted postdoctoral research at the Whitehead Institute for Biomedical Research, where he made significant contributions to the understanding of RNAi. In 2001, he joined the faculty at the University of Massachusetts Medical School, where he has continued his research on RNAi and related mechanisms.

Research Contributions

Phillip D. Zamore is best known for his work on the mechanisms of RNA interference, a process by which double-stranded RNA induces the degradation of messenger RNA (mRNA) in a sequence-specific manner. His research has elucidated key aspects of the RNAi pathway, including the roles of Dicer and Argonaute proteins.

Zamore's work has had significant implications for the development of RNA-based therapeutics. His research has contributed to the understanding of how small interfering RNAs (siRNAs) and microRNAs (miRNAs) can be used to regulate gene expression and treat various diseases.

Awards and Honors

Phillip D. Zamore has received numerous awards and honors for his contributions to molecular biology and genetics. These include the National Institutes of Health (NIH) Director's Pioneer Award and election to the American Academy of Arts and Sciences.

Personal Life

Phillip D. Zamore resides in Massachusetts with his family. He is an avid supporter of science education and frequently participates in outreach programs to promote interest in molecular biology and genetics among young students.

See Also

• RNA interference
• Dicer
• Argonaute
• University of Massachusetts Medical School
• David Bartel